Dr. Ling-Gang Wu's lab, Synaptic Transmission Section in the National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland is seeking one highly motivated postdoctoral fellow. The Wu lab studies molecular and biomechanical mechanisms of fusion and endocytosis of vesicles in the field of Neuroscience (synaptic transmission), endocrinology (hormone release in fight or flight response) and virology (SARS-CoV2 virus infection). The research focuses on the molecular mechanics underlying membrane dynamics, including vesicle docking, hemi-fusion, fusion pore opening, fusion pore closure, membrane curvature initiation, formation of W-shape pits, fission pore constriction, hemi-fission and fission. Advanced techniques, including super-resolution STED at ~30 nm resolution and MINFLUX nanoscopy at ~3 nm resolution, confocal and electron microscopy, cell molecular biology, electrophysiological techniques and computer simulation are used to visualize the above-mentioned membrane dynamics as well as protein and lipid molecules acting together in real time at the nanoscale to drive these membrane curvature dynamics in live cells.
Requirements
Applicants should have a Ph.D. in biology, biophysics, molecular biology, neuroscience, or virology. Desirable skills include: experience in either confocal imaging, super-resolution imaging, molecular biology, electrophysiology, electron microscopy and/or computer simulation; solid publication record; good verbal and written communication skills; and an ability to work effectively in a team-work environment with collaborators from different disciplines. Salary will be commensurate with experiences. Applications should include CV, representative publications, the names of three referees, cover letter detailing their qualification for this position, and research statement of what they would contribute to the laboratory.
Applications should be sent by email to Dr. Ling-Gang Wu at wul@ninds.nih.gov. The positions are available immediately and will remain open until filled.
NIH AND DHHS ARE EQUAL OPPORTUNITY EMPLOYERS