2023
Yadav, A; Matson, KJE; Lee, D; Alkaslasi, MR; Roome, RB; Ward, ME; Phatnani, H; Le Pichon, CE; Menon, V; Levine, AJ. (2023) A reproducible signature of cytoskeletal and ALS-related genes in human motoneurons. Neuron, 6: 3742. https://www.sciencedirect.com/science/article/pii/S0896627323008395?via%3Dihub
R. Brian Roome and Ariel J. Levine (2023). The Organization of Spinal Neurons: Insights from Single Cell RNA Sequencing. Current Opinion in Neurobiology, 82:102762. https://doi.org/10.1016/j.conb.2023.102762
Archana Yadav*, Kaya J.E. Matson*, Li Li, Isabelle Hua, Joana Petrescu, Kristy Kang, Mor R. Alkaslasi, Dylan I. Lee, Saadia Hasan, Ahmad Galuta, Annemarie Dedek, Sara Ameri, Jessica Parnell, Mohammad M. Alshardan, Feras Abbas Qumqumji, Saud M. Alhamad, Alick Pingbei Wang, Gaetan Poulen, Nicolas Lonjon, Florence Vachiery-Lahaye, Pallavi Gaur, Mike A. Nalls, Yue A. Qi, Michael E. Ward, Michael E. Hildebrand, Pierre-Francois Mery, Emmanuel Bourinet, Luc Bauchet, Eve C. Tsai, Hemali Phatnani, Claire E. Le Pichon, Vilas Menon#, Ariel J. Levine# (2023). A Cellular Taxonomy of the Adult Human Spinal Cord. Neuron 111:328 *equal contribution; #co-corresponding. https://doi.org/10.1016/j.neuron.2023.01.007
Gao, C., Gohel, C.A., Leng, Y., Goldman, D., Levine, A.J., Penzo, M.A. (2022) Molecular and spatial profiling of the paraventricular nucleus of the thalamus. eLife 12:e81818 doi: 10.7554/eLife.81818
Koch, SC; Levine, AJ. (2023) The Neuronal Cell Types of the Spinal Cord. Spinal Interneurons, Elsevier. https://doi.org/10.1016/B978-0-12-819260-3.00005-6
2022
Kathe, C. et al…Matson, K.J.E.;… Levine, A.J., Wagner, F.; Bloch, J.; Squair J.W.; Courtine, G. (2022) The Neurons That Restore Walking After Paralysis. Nature 611:540 doi: 10.1038/s41586-022-05385-7
Matson, K.J.E., Russ, D.E., Kathe, C., Maric, D., Hua, I., Maric, D., Ding, Y., Krynitsky, J., Pursley, R., Sathyamurthy, A., Squair, J.W., Levi, B.P., Courtine, G., and Levine, A.J. (2022). A Single Cell Atlas of Spared Tissue Below a Spinal Cord Injury Reveals Cellular Mechanisms of Plasticity. Nature Communications 13:5628 doi: 10.1038/s41467-022-33184-1
2021
Do Couto Nicola, F; Hua, I; Levine, AJ. (2021) Intersectional Genetic Tools to Study Skilled Reaching in Mice. Experimental Neurology. doi: 10.1016/j.expneurol.2021.11387
Squair, JW; Gautier, M; Kathe, C; Anderson, MA; James, ND; Hutson, T; Hudelle, R; Qaiser, T; Matson, KJE; Barraud, Q; Levine, AJ; La Manno, G; Skinnider, MA; Courtine, G. (2021) Confronting false discoveries in single-cell differential expression. Nature Communications, 12:5692. doi: 10.1038/s41467-021-25960-2
Russ, ED*; Patterson-Cross, RB*; Li, L; Koch, SC; Matson, KJE; Levine, AJ. (2021) A Harmonized Atlas of Spinal Cord Cell Types and Their Spatial Organization. Nature Communications, 12:5722. doi: 10.1038/s41467-021-25125-1
Barik, A; Sathyamurthy, A; Thompson, JH; Seltzer, M; Levine, AJ; Chesler AT. (2021) A spinoparabrachial circuit defined by Tacr1 expression drives pain. eLife 10:e61135. doi: 10.1038/s41467-021-25960-
Patterson-Cross, RB; Levine, AJ*; Menon, V*. (2021) Selecting single cell clustering parameter values using subsampling-based robustness metrics. In press BMC Bioinformatics. *co-corresponding. doi: 10.1186/s12859-021-03957-4
2020
Skinnider, MA; Squair, JW; Kathe, C; Anderson, MA; Gautier, M; Matson, KJE; Milano, M; Hutson, TH; Barraud, Q; Phillips, AA; Foster, LJ; La Manno, G; Levine, AJ; Courtine, G. (2020) Cell Type Prioritization in Single-Cell Data, Nature Biotechnology. doi: 10.1038/s41587-020-0605-1
Sathyamurthy, A; Barik, A; Dobrott, CI; Chesler, AT; Levine, AJ. (2020) Cerebellospinal neurons regulate motor performance and motor learning. Cell Reports, 31: 107595. doi: 10.1016/j.celrep.2020.107595
2019
Dobrott, CI; Sathyamurthy, A; Levine, AJ. (2019) Decoding Cell Type Diversity Within the Spinal Cord. Current Opinion in Physiology, 8:1-6. doi: 10.1016/j.cophys.2018.11.006
2018
Matson, KJE; Sathyamurthy, A; Johnson, KR; Kelly, MC; Kelley, MW; Levine, AJ. (2018) Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-Nucleus RNA Sequencing. Journal of Visualized Experiments, 140:e58413. doi: 10.3791/58413
Sathyamurthy, A*; Johnson, KR*; Matson, KEJ; Li, Li; Ryba, AR; Bergman, TB; Dobrott, CI; Kelly, MC; Kelley, MW; Levine, AJ. (2018) Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity During Behavior. Cell Reports, 22: 2216-2225. *equal contribution. doi: 10.1016/j.celrep.2018.02.003
Hayashi, M; Hinckley, CA; Driscoll, SP; Moore, NJ; Levine, AJ; Hilde, KL; Sharma, K; Pfaff, SL. (2018) Graded arrays of spinal and supraspinal V2a interneuron subtypes underlie forelimb and hindlimb motor control. Neuron, 97:869-884. doi: 10.1016/j.neuron.2018.01.023
2012-2016
Hilde, KL; Levine, AJ; Hinckley, CA; Hayashi, M; Montgomery, JM; Gullo, M; Driscoll, SP; Grosschedl, R; Kohwi, Y; Kohwi-Shigematsu, T; Pfaff, SL. (2016) Satb2 is required for the development of a spinal exteroceptive microcircuit that modulates limb position. Neuron, 91:763-776.
Pawar, K; Cummings, B; Thomas, A; Shea, L; Levine, A; Pfaff, S; Anderson, A (2015) Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: association with recovery of forelimb function. Biomaterials, 65:1-12.
Levine, AJ*, Hinckley, CA*, Hilde, KL, Driscoll, SP, Poon, TH, Montgomery, JM, Pfaff, SL (2014) Identification of a cellular node for motor control pathways. Nature Neuroscience, 17:586:593. *equal contribution
Levine, AJ; Lewallen, KA; Pfaff, SL. (2012) Spatial organization of cortical and spinal neurons controlling motor behavior. Current Opinions in Neurobiology, 22:812-21.