The Neurophysiology of Epilepsy Unit is part of the Surgical Neurology Branch of the NINDS. We perform extensive deep phenotyping of epilepsy patients undergoing evaluation at the NIH Clinical Center, including neurophysiologic (EEG and MEG) and structural and functional neuroimaging. We seek to improve our ability to identify where seizures start and to better understand how seizure activity spreads throughout the brain in order to improve the efficacy of targeted interventions in individual patients with drug-resistant focal epilepsy.