
The Neurosurgery Unit for Pituitary and Inheritable Diseases is part of the Surgical Neurology Branch of the NINDS. We are a translational science lab that integrates neurosurgery and science to address the morbidity arising from neuroendocrine tumors of the brain and spinal cord. These include sporadic pituitary tumors and inheritable tumors in VHL and NF2. We rely on syngeneic, pairwise comparisons of the transcriptome, epigenome, proteome and the metabolome to investigate mechanisms of tumor formation and progression.