Work in LFMI often makes use of animal models, especially rodents. This work is done in a manner that is consistent with all of the rules and regulations of the NINDS IACUC. Rodents are used for three types of studies:
1. Advancing non-invasive assessment of brain function using anatomical, functional, and molecular imaging techniques
2. Elucidating the regulation and control of cellular energy metabolism and the role of creatine kinase
3. Development of imaging techniques useful for analyzing transgenic mice to help with functional genomic studies
4. Understanding control of cerebral microcirculation
5. Establishing the marmoset as an animal modal for marmoset study of the brain
Active LFMI animal protocols:
Imaging Brain Function in Rats and Mice
Imaging Brain Plasticity in Rats and Mice
Manganese Based Radiotracers for PET Imaging in Rodents
Development of 7 Tesla MRI Methodology for Anatomical Functional and Spectroscopic Imaging of the Brain
MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle
Functional MRI in Awake Rodents
Breeding of Mice for Experiments in the LFMI
How to get started?
Work with animals in LFMI is done under the supervision of the NINDS IACUC and the NIH NMR Center Mouse Imaging Committee. For a detailed description of procedures that are followed prior to starting any animal studies in LFMI, please go to the NMRF web site.