Muscle and Nerve Disorders

Program Duration: 2-5 years

The fellowship program in muscle disorders trains pediatric and adult neurologists in inflammatory and genetic muscle and nerve diseases in preparation for an academic career. Muscle and Nerve Disorders Fellows have the opportunity to participate in conducting therapeutic clinical trials using genetic, pharmacological and biological approaches. A number of cohorts of patients with specific muscle and nerve disorders are followed, and a genetic outreach program is in place to identify and characterize pediatric and adult patients and their families with both new and previously known hereditary muscle and nerve diseases applying next generation genomic technologies in conjunction with extended phenotyping. The first year of this fellowship can be at the Johns Hopkins University Hospital as part of a JHU/NINDS joint neuromuscular fellowship program.

AREAS OF CURRENT RESEARCH

  • Congenital muscular dystrophies
  • Congenital myopathies
  • Inherited myopathies
  • Muscular dystrophies
  • Myofibrillar myopathies
  • Myotonic dystrophy
  • Inherited disorders of the peripheral nervous system and motor neuron
  • Muscle regeneration
  • Autoimmune muscle disease, including dermatomyositis, polymyositis, and statin-triggered necrotizing myopathy.
  • Inclusion Body Myositis

FACULTY and GME Page

Carsten Bönnemann, M.D., habil., Acting Chief, Neurogenetics Branch; Chief, Neuromuscular and Neurogenetic Disorders of Childhood Section, NINDS, carsten.bonnemann@nih.gov

A. Reghan Foley, M.D. MD(Res), Senior Research Physician, Neuromuscular and Neurogenetic Disorders of Childhood Section, Neurogenetics Branch, NINDS, reghan.foley@nih.gov

Christopher Grunseich, M.D., Senior Research Physician, Hereditary Neurological Disease Section, Neurogenetics Branch, NINDS, christopher.grunseich@nih.gov

Andrew Mammen, M.D., Ph.D., Unit Leader, Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulation, NIAMS, andrew.mammen@nih.gov